August 27, 2011 Island Crisis » Marijuana For Hard-To-Treat Brain Cancer
The authors of these investigations have accordingly derived that the administration of THC in combination with TMZ “enhanced autophagy” (programmed cell death) in malignant tissue. According to them, “The combined administration of THC, CBD, and TMZ remarkably reduced the growth of glioma xenografts … [and] produced a strong antitumoral action in both TMZ-sensitive and TMZ-resistant tumors. Altogether, our findings support that the combined administration of TMZ and cannabinoids could be therapeutically exploited for the management of GBM (gliobastoma multiforme).”
Earlier in the year 2006 a study was published in the British Journal of Cancer. This study had reported that the intra-tumoural administration of THC is associated with reduced tumor cell proliferation in two out of nine human subjects with GBM (which is highly resistant to conventional anti-cancer treatments).